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Leading Factors In Polycystic Kidney Disease (PKD)

Leading Factors In Polycystic Kidney Disease (PKD)Polycystic Kidney Disease (PKD) seriously affects people’s health and daily habits. To treat PKD better, we must learn the inducing factors of polycystic kidneys. Now let’s see what factors can result in polycystic kidney disease.

1. Gene mutation

The factors in the formation of embryo make gene mutation due to various factors, thus leading to PKD. This case is rare but it still can occur.

2. Infection

Infection can make your body internal environment become abnormal, which will induce cystic gene. In this case, this makes the internal active factors of cysts become strong. Thus, it increases the risk of cysts.

3. Congenital dysplasia

Because congenital dysplasia can lead to various illness or diseases, it can result in PKD.

4. Toxins

Toxins is one of the major factors for gene mutation and congenital dysplasia. Toxins of inducing PKD include pesticide, chemical agent, radioactive rays and pollution, etc.

How is the genetic law of adult polycystic kidney disease?

Autosomal dominant polycystic kidney disease (ADPKD) is known as adult polycystic kidney disease. This disease follows autosomal dominant familial law, namely:1. The risk between men and women is the same; 2. Father or mother has PKD, and the risk of children is below 50%. If parents both have this disease, the risk of children increases to 75%; 3. Children without cystic gene get married with opposite sex who has no disease, their children and generations do not suffer from PKD.

How is the genetic law of infantile polycystic kidney disease?

Autosomal recessive polycystic kidney disease (ARPKD) is also knowns as infantile polycystic kidney disease. Children are more likely to suffer from PKD when the parents both carry this gene. The morbidity risk is 25% and gene transfer rate is 50%. But parents have no disease, which is the meaning of recessive inheritance. Patients usually die after several hours of birth or days. Patients with mild conditions can live to be several years old or even be an adult.

If you have family heredity history of PKD, you should do regular test to diagnose whether you have polycystic kidney. The earlier you detect it, the better your therapeutic effect is. If you want to learn more information about PKD, you can talk with our experts or leave us a message to chinakidneytherapy@gmail.com.

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